Shaoxing Huawei Chemical Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cov tshuaj qib triphenylphosphine hauv Suav teb. Yog hais tias koj yuav mus yuav bulk tshuaj qib triphenylphosphine ua nyob rau hauv Suav teb, txais tos kom tau txais pricelist thiab hais los ntawm peb lub hoobkas. Tag nrho cov khoom customized yog nrog cov khoom zoo thiab cov nqi sib tw.

Pharmaceutical qib triphenylphosphine

Khoom Taw Qhia

Pharmaceutical grade triphenylphosphine yog ib qho kev cai -engineered organophosphorus khoom, tsim tshwj xeeb rau cov kev cai nruj ntawm niaj hnub kws tshuaj API thiab intermediate synthesis. Nws zoo nkaus li cov xim dawb los yog tawm -dawb crystalline hmoov, nrog rau cov tshuaj lom neeg ruaj khov nyob rau hauv ntev - lub sij hawm cia thiab batch ntau lawm tej yam kev mob, raws li zoo raws li precisely tswj cov tshuaj tiv thaiv kev ua ub no rau lub hom phiaj kws tshuaj synthesis txoj kev. Raws li cov khoom siv tseem ceeb tshaj plaws rau kev lag luam tshuaj, nws feem ntau ua haujlwm raws li cov tshuaj tiv thaiv tseem ceeb nruab nrab thiab universal catalytic ligand hauv kev tsim cov tshuaj intermediates thiab complex tshuaj molecules-xws li hluavtaws quinolone tshuaj tua kab mob, me me -molecule kinase inhibitor cov tshuaj tiv thaiv (PI, {7}). Nrog rau kev sib raug zoo nrog kev lag luam - teev cov txheej txheem tshuaj ntau lawm thiab batch- rau- cov khoom sib xws, cov tshuaj qib triphenylphosphine no tau tsim kom ntev -lub sij hawm ruaj khov muab kev koom tes nrog ntau dua 90% ntawm domestic GMP-cov ntaub ntawv pov thawj kws tshuaj 5} cov khoom siv raw khoom, kev txhawb nqa ob qho tib si Cov tshuaj tshiab tshiab R&D thiab loj - teev cov tshuaj siv tshuaj ntau lawm.

Khoom Paub meej

Tsim thiab soj ntsuam nruj raws li cov qauv kev lag luam thoob ntiaj teb, GMP cov lus qhia tshwj xeeb, thiab ICH Q7 cov lus qhia rau API kev tsim khoom, cov khoom no siv triphenylphosphine raws li nws cov ntsiab lus tseem ceeb, nrog rau kev lees paub yam tsawg kawg nkaus purity ntawm ntau dua lossis sib npaug li 99.5%, nruj tswj cov kab impurity theem (xws li cov tshuaj lom neeg cov tshuaj lom neeg, cov kev txwv hnyav thiab cov kev txwv tsis pub muaj. raws li ICH Q3 cov lus qhia), thiab cov khoom siv lub cev thiab tshuaj zoo ib yam thoob plaws txhua pawg. Nws yog insoluble nyob rau hauv dej tsis tau tag nrho miscible nyob rau hauv cov organic solvents siv nyob rau hauv tshuaj synthesis, xws li ethanol, benzene, thiab tetrahydrofuran, nrog ntev -lub sij hawm txee ruaj khov nyob rau hauv kev pom zoo cia tej yam kev mob thiab tsis irritating tsw- ua tau raws li qhov xav tau heev rau raw khoom purity, kev nyab xeeb, thiab traceability nyob rau hauv cov tshuaj ntau lawm. triphenylphosphine ua raws li qib siab -kev xaiv txo tus neeg sawv cev, homogeneous catalyst ligand, thiab cov khoom siv hluavtaws tseem ceeb hauv kev tsim tshuaj nruab nrab. Nws tuaj yeem txhim kho qhov kev hloov pauv ntawm cov tshuaj synthesis cov tshuaj tiv thaiv, txhim kho cov stereoselectivity ntawm lub hom phiaj chiral cov khoom, txo qhov tshwm sim ntawm cov kev xav tsis zoo sab, thiab txo qhov nyuaj ntawm downstream purification. Muaj feem xyuam rau ntau-theem synthesis ntawm ntau yam siab{11}}kawg kws tshuaj intermediates, nws plays lub luag hauj lwm irreplaceable nyob rau hauv enabling lub stereoselective tsim complex carbon-carbon thiab carbon-heteroatom bonds nyob rau hauv intricate tshuaj molecule synthesis.

Product Quality Assurance

Txhawm rau kom ntseeg tau tias cov tshuaj qib triphenylphosphine ua tau raws li cov qauv kev cai siab ntawm kev lag luam kws tshuaj thoob ntiaj teb thiab cov khoom siv nruj heev ntawm peb cov koom tes lag luam, peb tau tsim qhov kaw -loop, batch-traceable quality management system (QMS) raws li GMP cov cai. Tag nrho cov khoom siv raw khoom tau dhau los ua qhov kev tswj xyuas zoo (IQC) kev ntsuam xyuas tawm tsam cov tshuaj qib tshwj xeeb, tsuas yog cov khoom tsim nyog tso tawm rau kev tsim khoom. Tag nrho cov txheej txheem tsim khoom yog ua tiav hauv D-chaw ua haujlwm huv chav kawm, nruj me ntsis ua raws li cov txheej txheem kev ua haujlwm thiab ICH cov lus qhia, nrog rau lub sijhawm tiag tiag hauv -txheej txheem kev tswj hwm (IPQC) ntawm txhua qhov tseem ceeb ntawm cov khoom lag luam txhawm rau tshem tawm txoj kev pheej hmoo ntawm kev hla - kis kab mob thiab impurity introduction.Txhua batche of pharmaceuticals yuav tsum muaj cov tshuaj passhhen multi- Performance index tiav kev tswj hwm zoo (FQC) kev ntsuam xyuas ua ntej tawm hauv lub Hoobkas, nrog rau kev tshuaj xyuas cov ntsiab lus tseem ceeb suav nrog kev ua haujlwm purity, impurity profile, gene toxic impurity txwv, cov tshuaj tiv thaiv hauv kev simulated pharmaceutical synthesis, noo noo cov ntsiab lus, thiab residual hnyav theem. Peb muab ib daim ntawv ua tiav, batch{11}}cov ntawv pov thawj tshwj xeeb ntawm Kev Ntsuam Xyuas (CoA) rau txhua qhov khoom xa tuaj, nrog rau tag nrho cov ntaub ntawv khaws cia rau yam tsawg kawg ntawm 5 xyoo rau kev tswj hwm kev lag luam tshuaj, kom paub meej tias tag nrho cov khoom tsim nyog thiab kev ua raws cai. Qhov xoom no -kev sib haum xeeb, GMP- ua raws li kev tswj hwm zoo tau txais kev ntseeg siab ntev ntev thiab kev lees paub ntawm ntau dua 90% ntawm GMP hauv tsev- ntawv pov thawj kev lag luam kws tshuaj, tso lub hauv paus ruaj khov rau kev ruaj khov, ntev ntev - kev koom tes.